Free tool · Honest math

How much will you actually spend on GLP-1s this year?

Compare Wegovy, Zepbound, Mounjaro, Ozempic, and OPTML compounded, at real prices, not promo. Pick your situation, see the 12-month total side-by-side.

OPTML retail is the same for full-dose and microdose, you pay by molecule, not by milligram.

~75% of commercial plans don't cover GLP-1s for weight loss without diabetes, this is the most common case.

Pricing notes. Competitor cash and savings-card prices reflect publicly listed retail and Novo Nordisk / Eli Lilly savings program terms as of 2026. OPTML pricing is all-inclusive: medication, physician oversight, supplies, and shipping. Labs ($80) are billed separately if you need a fresh panel. Compounded semaglutide and tirzepatide use active pharmaceutical ingredients that are chemically identical to those used in the FDA-approved branded products, prepared by licensed 503A pharmacies under USP <797> sterility standards. Compounded preparations are not FDA-approved; the FDA does not verify the safety, effectiveness, or quality of compounded drugs.

Educational purposes only. The GLP-1 Cost Calculator provides educational estimates based on published clinical formulas and peer-reviewed research. It is not medical advice, does not constitute a prescription, and is not a substitute for evaluation by a licensed clinician. All medical decisions, including any treatment, medication, or dosing recommendations, are made exclusively by a U.S. licensed physician after individual patient evaluation through OPTML's intake process.
Methodology & Sources Click here for the formulas, datasets, and peer-reviewed studies behind this tool View details ↓Hide ↑

How this tool calculates

The cost comparison reflects publicly listed retail prices for FDA-approved branded GLP-1 medications (Wegovy, Zepbound, Ozempic, Mounjaro) versus OPTML's flat compounded-medication subscription prices. Retail prices change over time; figures are sourced from manufacturer-published list prices and major pharmacy retail rates.

Peer-reviewed sources

  1. 1.Novo Nordisk. Wegovy List Price Disclosure. novonordisk.com.
  2. 2.Eli Lilly. Zepbound List Price Disclosure. lilly.com.
  3. 3.Goldman DP, Joyce GF, Zheng Y. Prescription Drug Cost Sharing: Associations With Medication and Medical Utilization and Spending and Health. JAMA. 2007;298(1):61-69.
  4. 4.Conti RM, Padula WV, Becker RV. The Impact of Recent Drug Pricing Reforms. Health Aff (Millwood). 2023;42(11):1499-1506.

Important. This tool is provided for educational purposes only and does not constitute medical advice, diagnosis, or treatment. The tool does not prescribe medication, recommend specific dosing, or substitute for clinical evaluation. Compounded medications referenced anywhere on this site are not FDA-approved; the FDA does not verify the safety, effectiveness, or quality of compounded drugs. Treatment decisions are made only by a licensed U.S. physician after individual patient evaluation.