GLP-1s. Hormones. Longevity. Optimize everything. Find my protocol →
★★★★★ 4.9 200,000+ patients across our provider network

Be optimal.Be optimal.

Physician-led GLP-1, hormone, and longevity protocols.
Delivered to your door.

  • Prescribed by U.S. licensed MDs
  • Compounded at licensed 503A pharmacies
  • 2–3 day shipping to all 50 states
  • No insurance, no hidden fees, cancel anytime
OPTML compounded GLP-1, TRT, and NAD+ vials and pills
For women

GLP-1s

Start now → Athletic couple seated post-workout in OPTML's warm-lit studio
For men

TRT & enclomiphene

Start now →
Included with every protocol
  • Free physician consultation
  • Board-certified physicians
  • Unlimited provider messaging
  • Free 2-3 day shipping
  • Discreet packaging
  • Cancel anytime
  • No insurance needed
  • Licensed in all 50 states

What we treat

--% Real Science, Real Results

On average, people on Tirzepatide lose 20% of their body weight in 12 months.*

Current weight
220lbs
Weight you could lose
44lbs

*Clinical trial data is from studies of FDA-approved tirzepatide (Zepbound®) in non-diabetic patients with obesity, paired with healthy lifestyle changes. Compounded preparations are not FDA-approved; the FDA does not verify the safety, effectiveness, or quality of compounded drugs. Individual results vary.

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How it works

Personalized care, made effortless.

Science-backed treatment, delivered discreetly, with ongoing support every step of the way.

Man taking online health visit on phone
01

Place your order

Pick your treatment and check out online in minutes. No insurance needed.

optml care chat with U.S. licensed physician
02

Doctor consultation

A U.S. licensed physician reviews your case and writes your protocol if you’re a fit.

optml branded shipping box on countertop
03

Delivered + ongoing care

Ships discreetly in 2–3 days. Your care team is a message away anytime.

Private & secure

Your data is encrypted and always protected.

Physician-led

U.S. licensed physicians at every step.

Science-backed

Rooted in science. Backed by results.

Discreet delivery

Ships to your door in unbranded packaging.

Lab testing · One blood draw

Premium
blood testing.
Clear next steps.

One draw. 160+ biomarkers. Premium panels delivered direct — clear numbers, not a portal of unread results.

See panels and pricing

Basic Panels

25+ markers

Hormones, metabolic, lipids — the optimization foundation.

Full Blood Panels

65+ markers

Adds thyroid, inflammation, vitamins, kidney — full organ-system view.

Apex Panel

160+ markers

Adds cancer screening, heavy metals, autoimmune — the deepest panel available.
160+
biomarkers
CLIA-certified
labs
Lab-direct
results
Secure
& private

CLIA-certified labs. Premium panels.

Trusted by 200,000+ patients across our provider network.

Labs by optml

Know your baseline.

Premium blood testing with clear next steps.

Panels from 25 to 160 biomarkers. No insurance, no membership. Drawn at any Quest Diagnostics or LabCorp location nationwide, reviewed by a U.S.-licensed physician.

The flagship blood panel · 160+ biomarkers

The Apex Panel.

The world’s most advanced blood panel.

No diagnostic outside a hospital admission goes deeper. 160+ biomarkers across every major organ system — heart, hormones, metabolism, cancer screening, heavy metals, autoimmune — in a single blood draw. No membership, no waiting room.

  • Heart & cardiovascular
  • Hormones (full panel)
  • Metabolic & insulin
  • Thyroid (full)
  • Liver & pancreas
  • Kidney & urinalysis
  • Inflammation & immunity
  • Heavy metals (lead, mercury)
  • Vitamins & nutrients
  • Cancer screening (PSA)
  • Stress & aging markers
  • Autoimmune (RF, TPO, Tg)
CLIA-certified labs Single blood draw 160+ biomarkers Every major organ system
$599one-time · no subscription
Learn more about the Apex Panel Order it now →
Targeted

TRT Panel

For men on testosterone therapy. Total testosterone, hematocrit, LH, PSA.

$75Order →
Targeted

GLP-1 Comprehensive

For patients on semaglutide or tirzepatide. Metabolic, insulin, A1c, lipids, B12, vitamin D.

$99Order →
Targeted

Enhanced Metabolic

GLP-1 Comprehensive + amylase & lipase. For long-term GLP-1 patients tracking pancreatic safety.

$119Order →
Most popular · Men

Optimized Health, Male

The standard starting panel for men. Full hormones, metabolic, lipids, thyroid, prostate.

$199Order →
Most popular · Women

Optimized Health, Female

The standard starting panel for women. Full hormones (incl. ultrasensitive estradiol & progesterone), metabolic, thyroid.

$229Order →
Advanced · Men

Longevity, Male

Optimized Health + homocysteine, hs-CRP, cortisol, sed rate, advanced lipids, RBC magnesium.

$229Order →
Advanced · Women

Longevity, Female

Optimized Health + homocysteine, hs-CRP, cortisol, estrone, advanced lipids, RBC magnesium.

$249Order →
Flagship · 160+ markers

The Apex Panel

Our most comprehensive blood panel. Hormones, metabolic, thyroid, heavy metals, cancer screening, autoimmune.

$599Order →

Drawn at any Quest Diagnostics nationwide. Run at CLIA-certified labs. Results returned in 3-5 business days with normal-range context. Cash-pay; HSA/FSA accepted. See full panel details →

200K+
Patients treated across our provider network
98%
Satisfaction rate across our provider network
48hr
Average delivery
24/7
Provider support
Couples are getting healthier on OPTML

Get healthier,
together on optml

In SURMOUNT-1 (branded tirzepatide 15mg):
20.9%
of body weight over 72 weeks1
In STEP-1 (branded semaglutide 2.4mg):
14.9%
of body weight over 68 weeks2
Start your journey

Clinical-trial results

Physician-led GLP-1 protocols, paired with nutrition and training, deliver weight-loss outcomes that diet and exercise alone consistently fall short of.

1SURMOUNT-1 (Jastreboff et al., NEJM 2022): tirzepatide 15 mg, −20.9% body weight at 72 weeks vs −3.1% placebo. 2STEP 1 (Wilding et al., NEJM 2021): semaglutide 2.4 mg, −14.9% body weight at 68 weeks vs −2.4% placebo. Adults with obesity or overweight plus a weight-related condition. Individual results vary.

Compounded-drug disclosure

Both trials studied the FDA-approved branded products (Zepbound®/Mounjaro®, Wegovy®/Ozempic®). OPTML prescribes compounded versions of the same active ingredients; compounded preparations are not FDA-approved, and the FDA does not verify the safety, effectiveness, or quality of compounded drugs.

Meet your care team

Every OPTML patient is seen by a U.S. licensed physician. No nurse-practitioner-only protocols. No pharmacy-on-autopilot.

← Swipe · Scroll →

Dr. Takashi Nakamura, MD, FACEP
Dr. Takashi Nakamura
MD · FACEP

Chief Medical Officer. Board-certified emergency medicine physician with 11+ years of clinical practice.

Dr. Laurie J. Mercier, MD
Dr. Laurie J. Mercier
MD · Family Medicine

Medical Director. Board-certified family physician with 30+ years of clinical experience.

Dr. Stephen MacDade, MD
Dr. Stephen MacDade
MD · Emergency Medicine

Board-certified emergency medicine physician with 10+ years of clinical experience. Telehealth, acute care, and men’s health.

Dr. Scott Sanderson, MD
Dr. Scott Sanderson
MD · Emergency Medicine

Board-certified emergency medicine physician with a background in military medicine. Aesthetic and regenerative care.

Kimberli Hastings, MSN, RN, NP
Kimberli Hastings
MSN · RN · NP

Family Nurse Practitioner specializing in family medicine and mental health. Clinical experience since 2019.

Board-certified U.S.-licensed clinicians, available in all 50 states. See the full care team →

Free · No login · No email

19 free tools built on peer-reviewed research.

Calculators, scores, and decoders grounded in published clinical formulas — Mifflin-St Jeor, Hodgdon-Beckett, the Greene Climacteric Scale, Endocrine Society reference ranges, and more. Decode your labs, score your symptoms, model your dose, project your savings — in under a minute.

Most popular this week

Start with these.

See all 19
Start here

Find My Protocol

60-sec personalized plan
SymptomsLabsGoalsProtocol
GLP-1

GLP-1 Dose Calculator

Dial in your starting dose
Est. weight loss
22%
in 6 months
 For women

Perimenopause Score

Greene Climacteric Scale
23 / 63 · Moderate
Labs

Lab Decoder

Turn labs into answers
41 biomarkers
95% optimized
3 flagged · protocol matched

Health guide

Complete a 5-minute online health questionnaire. A licensed provider reviews your information and, if appropriate, prescribes treatment. Your medication ships to your door in discreet packaging within 2-3 days. You can message your provider anytime.

Yes. All treatments are prescribed by US-licensed healthcare providers and dispensed from FDA-regulated pharmacies. Your provider is available for follow-ups and adjustments throughout your treatment.

No. Our pricing is transparent and all-inclusive. You pay one monthly price that covers your provider consultation, medication, and shipping. No insurance required, no copays, no surprise bills.

Most patients notice changes within 2-4 weeks on GLP-1 medications. Appetite suppression often begins within the first week. TRT patients typically feel improvements in energy and mood within 3-6 weeks. Individual results vary.

Your provider will work with you to adjust your treatment plan. If a medication isn't right for you, they can recommend alternatives. You can cancel anytime, no long-term contracts.

Absolutely. All health information is HIPAA-protected. Medications arrive in plain, unmarked packaging. Your treatment is completely confidential.

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Weight Management

Semaglutide

A GLP-1 receptor agonist that works with the body’s natural hunger signals. In the STEP-1 trial of FDA-approved branded semaglutide (Wegovy® 2.4 mg weekly), participants averaged a 14.9% body-weight reduction at 68 weeks. One injection per week. Compounded preparations are not FDA-approved.

Get Started
Semaglutide vial
Why it works

The science is simple

⚙

Clinically Proven

FDA-studied. Significant, sustained weight reduction across diverse populations.

⏱

Once a Week

One small injection per week. No daily pills. No complicated routines.

♥

Beyond Weight Loss

Improves blood sugar, cardiovascular markers, and inflammatory biomarkers.

Couple hiking

How it works

Semaglutide mimics GLP-1, a natural hormone that regulates appetite. You feel full sooner. Cravings disappear. Weight comes off steadily.

  • Slows gastric emptying, you stay full longer
  • Reduces appetite signals in the brain
  • Improves insulin sensitivity
  • Steady, predictable rate of weight reduction

Ready to start?

5-minute questionnaire. Provider review. Medication at your door in 48 hours.

Get Started
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Weight Management

Tirzepatide

The first dual GIP and GLP-1 receptor agonist. Two pathways. One injection per week. The most modern class of weight-management medication.

Get Started
Tirzepatide vial
Why Tirzepatide

Next-generation weight loss

⚡

Dual Action

Targets both GIP and GLP-1 receptors simultaneously. Superior efficacy.

📈

22% Weight Loss

The highest weight reduction of any incretin therapy studied to date.

♥

Total Health

Improvements in A1c, blood pressure, triglycerides, and cardiovascular risk.

Experience the difference

See if Tirzepatide is right for you. Quick online consultation.

Get Started
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Longevity

NAD+

The coenzyme your cells need for energy, repair, and healthy aging. NAD+ levels drop 50% between ages 40-60. Restore them with subcutaneous injections.

Get Started
NAD+
Two delivery methods

Choose your protocol

💉

Subcutaneous Injection

Higher bioavailability. Maximum NAD+ levels. Self-administered at home in seconds, weekly or twice-weekly.

⚡

Cellular Energy

Essential for mitochondrial function and ATP production.

🔄

DNA Repair

Activates sirtuins and PARPs for genomic stability.

🧠

Cognitive Clarity

Sharper focus, better memory, enhanced brain energy.

Invest in your cells

Start your NAD+ protocol. Subcutaneous injections — $179/mo or $489 every 3 months.

Get Started
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Hormone Optimization

Testosterone Replacement

Tired all the time? Losing muscle? Brain fog that won't lift? Low testosterone affects everything. Our lab-driven TRT protocols are tailored to your body.

Get Started
Testosterone optimization
Symptoms

Sound familiar?

😢

Constant Fatigue

You sleep 8 hours and still feel exhausted. Coffee isn't cutting it anymore.

😤

Brain Fog

Can't focus. Can't remember things. Feel like you're operating at 60%.

💪

Losing Muscle

Working out but getting weaker. Gaining fat where you never used to.

Lab bloodwork

Everything starts with labs

No guessing. Every TRT protocol starts with comprehensive bloodwork. Your provider designs your protocol, then monitors and adjusts based on regular lab results.

  • Comprehensive pre-treatment blood panel
  • Individualized dosing for your body
  • Regular follow-up labs and adjustments
  • PSA and hematocrit monitoring

Get your energy back

Start with labs. Get your protocol. Feel the difference.

Get Started
← Back
Hormone Optimization

Enclomiphene

Want higher testosterone without shutting down your natural production? Enclomiphene stimulates your body's own T through the HPG axis. Fertility preserved. One daily pill.

Get Started
Enclomiphene capsules
Benefits

Testosterone, naturally

🔐

Fertility Safe

Unlike TRT, enclomiphene maintains and may improve sperm production.

⚡

Natural Production

Your body makes the testosterone. We just tell it to make more.

💊

One Daily Pill

No injections. No complicated protocols. Simple oral dosing.

Boost T naturally

Find out if enclomiphene is right for your goals.

Get Started
Prescribed by U.S. physicians No insurance
Lab Panels · By OPTML
★★★★★ 4.9 · 12,000+ panels read by our provider network

The definitive read on your health.

Comprehensive physician-ordered panels, drawn at any Quest or Labcorp in the country. Every marker reviewed by a U.S.-licensed physician with a protocol built for you.

160+ biomarkers CLIA-certified labs HSA / FSA eligible

Start your free assessment Find my panel →
160+
Biomarkers analyzed
2,200+
U.S. draw locations
12
Organ systems mapped
Your Health Score
87% Optimal
Total Testosterone Optimal
645 ng/dL
3001000
Fasting Glucose Optimal
82 mg/dL
JanFebMarAprMayJun
C-Reactive Protein Low
0.6 mg/L
03.0
Vitamin D Optimal
58 ng/mL
20100
Ferritin Optimal
142 ng/mL
30300
Clinical Standards
CLIA-certified labs HIPAA-compliant records LegitScript verified Board-certified oversight
The Library

From 4 markers to 160. Pick the depth that fits your goal.

Eight panels. One for every stage of optimization — from focused therapy tracking to a complete annual deep-dive.

0 markers TRT Panel $75 For men on testosterone therapy 0 markers GLP-1 Comprehensive $99 For patients on semaglutide / tirzepatide Most ordered 0 markers Optimized Health from $199 The standard starting panel 0 markers Longevity from $229 Advanced inflammation + cortisol Flagship 0 markers The Apex Panel $599 Every system, one blood draw
Not sure which panel is right for you? Take the 30-second match quiz
The System

A guided path from lab draw to protocol.

No menus. No guessing. You complete a short medical intake, a physician orders the right panel, and you receive a personalized protocol based on your results.

01

Take the assessment

A 4-minute intake covering symptoms, history, medications, and goals.

02

Physician orders labs

A licensed U.S. physician reviews your intake and orders the appropriate panel.

03

Draw at Quest or Labcorp

Walk into any of 2,200+ locations. No appointment. Usually in and out in 15 minutes.

04

Receive your protocol

Every marker returned with normal-range context — premium panels, not a portal of unread numbers.

Labs by OPTML · The Flagship Panel

The most advanced blood panel in the world.

160+ biomarkers across 12 organ systems, drawn in a single sitting at any Quest in the country. The most detailed picture of your health available outside a hospital admission — with normal-range context for every marker, reviewed by a physician. No membership. No subscription.

160+ biomarkers · 12 systems · one blood draw

The Apex Panel

The world’s most advanced blood panel.

No diagnostic outside a hospital admission goes deeper. 160+ biomarkers across every major organ system — heart, hormones, metabolism, cancer screening, heavy metals, autoimmune — in a single blood draw. No membership, no waiting room.

Physician-reviewed protocol Every marker reviewed by a U.S.-licensed MD
Normal-range context Every number with optimal-vs-typical context
3-5 day turnaround Results returned with full protocol & plan
Cash-pay friendly HSA / FSA accepted · no insurance hassle
  • Heart & cardiovascular
  • Hormones (full panel)
  • Metabolic & insulin
  • Thyroid (full)
  • Liver & pancreas
  • Kidney & urinalysis
  • Inflammation & immunity
  • Heavy metals (lead, mercury)
  • Vitamins & nutrients
  • Cancer screening (PSA)
  • Stress & aging markers
  • Autoimmune (RF, TPO, Tg)
CLIA-certified labs Single blood draw 160+ biomarkers Every major organ system
$599
one-time · no subscription
Learn more about the Apex Panel Order it now →
  • Drawn at any Quest Diagnostics nationwide
  • CLIA-certified labs · Lab-direct results
  • Physician-reviewed protocol returned to you
  • Cash-pay · HSA / FSA accepted
Explore the library

Eight panels. One matches your goal.

Targeted · comprehensive · flagship — each panel is physician-ordered and drawn at any Quest or LabCorp in the country.

Drawn at a lab near you

7,500+ draw sites within 10 miles of you.

Walk into any Quest or LabCorp location nationwide. Drop your ZIP and we’ll surface every draw site within 10 miles.

Live partner network · 7,500+ Quest, LabCorp + hospital locations

Find your panel · 30-second match

Answer 2 questions. We’ll match you to the exact panel you need.

Most patients overspend or under-test. This points you to the panel that gives you the most signal for your specific goal — not the most billable one.

Step 1 of 2

What are you optimizing?

Step 2 of 2

Which describes you?

Your match
Labs by OPTML · The Full Library

Eight panels. One that’s right for you.

Most new patients begin with Optimized Health. If you’re on TRT or a GLP-1, start with the matched targeted panel. Longevity adds inflammation, cortisol, and advanced cardiovascular markers. The Apex Panel covers it all.

Foundation · Targeted

For TRT patients

TRT Panel

For men on testosterone therapy. Tracks the four numbers your physician needs to titrate your dose safely.

$75 / panel
  • Testosterone, Total (Immunoassay)
  • Hematocrit (CBC)
  • Luteinizing Hormone (LH)
  • PSA, Total
Order panel
For GLP-1 patients

GLP-1 Comprehensive

For patients on semaglutide or tirzepatide. Tracks metabolic health, insulin sensitivity, and nutrient status while on therapy.

$99 / panel
  • Comprehensive Metabolic Panel + GGT
  • Hemoglobin A1c, Insulin, Triglycerides
  • Lipid Panel (Standard)
  • Vitamin D 25-Hydroxy, Vitamin B12
Order panel
For long-term GLP-1

Enhanced Metabolic

GLP-1 Comprehensive plus pancreatic enzymes. For patients on long-term GLP-1 therapy who need ongoing pancreatic monitoring.

$119 / panel
  • Comprehensive Metabolic Panel + GGT
  • Amylase & Lipase (pancreatic enzymes)
  • Insulin, Triglycerides, Lipid Panel
  • Vitamin D, Vitamin B12
Order panel

Comprehensive · Sex-specific

Most ordered · Men
Optimized Health

Optimized Health, Male

The standard starting panel for men. Full hormones, metabolic, lipids, thyroid, and prostate.

$199 / panel
  • Testosterone (Free, Bioavailable, Total)
  • SHBG, Estradiol, LH, TSH
  • PSA Free & Total, Cholesterol
  • CBC, CMP, Hemoglobin A1c
Order panel
Most ordered · Women
Optimized Health

Optimized Health, Female

The standard starting panel for women. Full hormones (incl. ultrasensitive estradiol), metabolic, thyroid.

$229 / panel
  • Testosterone (Free, Total via MS), SHBG
  • Estradiol Ultrasensitive (LC/MS), Progesterone
  • FSH, LH, TSH, DHEA-S
  • CBC, CMP, Cholesterol, A1c
Order panel
Advanced · Men

Longevity, Male

Optimized Health plus advanced inflammation, cortisol, vitamin D, and red-cell magnesium, for patients tracking trends year over year.

$229 / panel
  • Testosterone (Free, Bioavailable, Total via MS)
  • Homocysteine, hs-CRP, Sed Rate, Cortisol
  • GGT, Vitamin D, DHEA-S, Magnesium (RBC)
  • Lipid Panel with Ratios, VLDL, A1c, CMP, CBC
Order panel
Advanced · Women

Longevity, Female

Optimized Health plus advanced inflammation, cortisol, estrone, and red-cell magnesium, for patients tracking trends year over year.

$249 / panel
  • Estradiol, Estrone, DHEA-S
  • Homocysteine, hs-CRP, Sed Rate, Cortisol
  • GGT, Vitamin D, Magnesium (RBC)
  • Lipid Panel with Ratios, VLDL, A1c, CMP, CBC
Order panel
The next step

Your numbers. Delivered direct.

Pick the panel that fits your goals. We order the lab work, you draw at any Quest, results return within 3-5 business days.

Start your free assessment
Eligibility confirmed after intake. No charge until you qualify. Not sure which panel is right for you? Take the 30-second match
Questions

What to expect.

Direct answers to the questions patients ask most often before starting.

Is this covered by insurance?

No. OPTML is a cash-pay system, prices shown are final. Many patients use HSA or FSA funds.

Where do I get my blood drawn?

At any Quest or Labcorp in the U.S. (2,200+ locations). Your physician sends the order electronically before you walk in.

How soon will I get results?

Results return within 3-5 business days of the draw. You receive every marker with normal-range context — clear numbers, no gatekeeping.

Who reviews my results?

A U.S.-licensed, board-certified physician. Every panel is reviewed individually, no algorithms.

Available in 50 states

Confirm OPTML ships to your zip code.

Real-time check against our 50-state provider network. Takes 2 seconds.

ZIP