Liver system

Alkaline Phosphatase (ALP)

ALP

An enzyme from liver, bile ducts, and bone.

What is it

Alkaline Phosphatase (ALP) — in plain English.

Alkaline phosphatase is found in liver, bile ducts, bone, and intestine. Its source can be distinguished by isoenzyme testing or accompanying liver/bone markers.

Why it's measured

What ALP can reveal.

ALP has been used in evaluating bile flow obstruction and bone turnover in clinical research.

Reference range

Where most laboratories draw the standard line.

Standard laboratory reference

44 – 147 U/L

Reference ranges vary by laboratory. Your individual reference range will appear on your test report and should be interpreted by your physician in the context of your overall health profile.

What results may indicate

Higher vs. lower ALP — at a high level.

Elevated

Has been associated with bile duct obstruction, certain bone conditions, and pregnancy in research literature.

Lower

May reflect zinc deficiency or certain rare conditions.

These associations are general. They are not a personal diagnosis or prediction. Discuss your individual results with your physician in the context of your full health profile.

When it's measured

When ALP is typically run.

Part of standard liver panels.

Related markers

Often measured alongside ALP.

Common questions

Questions people ask about Alkaline Phosphatase (ALP)

What is Alkaline Phosphatase (ALP)?

Alkaline phosphatase is found in liver, bile ducts, bone, and intestine. Its source can be distinguished by isoenzyme testing or accompanying liver/bone markers.

Why is Alkaline Phosphatase (ALP) measured?

It's one of the markers used to build a fuller picture of your health. On its own it tells you very little, so it's most informative when reviewed alongside related markers.

How is Alkaline Phosphatase (ALP) tested?

It's measured from a standard blood draw at Quest or LabCorp. Alkaline Phosphatase (ALP) is one of the markers included in the OPTML Apex Panel, where your results are read across systems and reviewed by a U.S.-licensed physician.

What should I do with my Alkaline Phosphatase (ALP) result?

Reference ranges vary by laboratory, and a single value rarely tells the whole story. Review your result with a physician in the context of your other markers, symptoms, and history.

Not sure which panel is right for you?

Alkaline Phosphatase (ALP) is one signal among many. Answer a few quick questions and we’ll point you to the panel that fits.

Measured in

ALP is one of 160 biomarkers in the Apex Panel.

A complete look at your heart, hormones, metabolism, inflammation, and longevity systems — drawn at Quest or LabCorp, reviewed by a U.S.-licensed physician.

Explore the Apex Panel
160 biomarkers13 body systemsPhysician-reviewed
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This information is for general educational purposes only and is not medical advice. Lab results alone are not intended to diagnose, treat, or cure any condition and do not replace the advice of a healthcare provider. OPTML does not offer medical advice, a diagnosis, medical treatment, or any form of medical opinion.