Liver system

AST (Aspartate Aminotransferase)

AST

A liver and muscle enzyme — used alongside ALT in liver evaluation.

What is it

AST (Aspartate Aminotransferase) — in plain English.

AST is found in liver, heart, and muscle tissue. Elevation can reflect injury to any of these tissues, so AST is interpreted alongside ALT for liver-specific context.

Why it's measured

What AST can reveal.

AST has been used in liver evaluation, with the AST:ALT ratio providing additional clinical information in research literature.

Reference range

Where most laboratories draw the standard line.

Standard laboratory reference

< 40 U/L

Reference ranges vary by laboratory. Your individual reference range will appear on your test report and should be interpreted by your physician in the context of your overall health profile.

What results may indicate

Higher vs. lower AST — at a high level.

Elevated

Has been associated with liver injury, muscle injury, and certain cardiac conditions in research literature.

Lower

Is generally considered favorable.

These associations are general. They are not a personal diagnosis or prediction. Discuss your individual results with your physician in the context of your full health profile.

When it's measured

When AST is typically run.

Part of standard liver panels.

Related markers

Often measured alongside AST.

Common questions

Questions people ask about AST (Aspartate Aminotransferase)

What is AST (Aspartate Aminotransferase)?

AST is found in liver, heart, and muscle tissue. Elevation can reflect injury to any of these tissues, so AST is interpreted alongside ALT for liver-specific context.

Why is AST (Aspartate Aminotransferase) measured?

It's one of the markers used to build a fuller picture of your health. On its own it tells you very little, so it's most informative when reviewed alongside related markers.

How is AST (Aspartate Aminotransferase) tested?

It's measured from a standard blood draw at Quest or LabCorp. AST (Aspartate Aminotransferase) is one of the markers included in the OPTML Apex Panel, where your results are read across systems and reviewed by a U.S.-licensed physician.

What should I do with my AST (Aspartate Aminotransferase) result?

Reference ranges vary by laboratory, and a single value rarely tells the whole story. Review your result with a physician in the context of your other markers, symptoms, and history.

Not sure which panel is right for you?

AST (Aspartate Aminotransferase) is one signal among many. Answer a few quick questions and we’ll point you to the panel that fits.

Measured in

AST is one of 160 biomarkers in the Apex Panel.

A complete look at your heart, hormones, metabolism, inflammation, and longevity systems — drawn at Quest or LabCorp, reviewed by a U.S.-licensed physician.

Explore the Apex Panel
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This information is for general educational purposes only and is not medical advice. Lab results alone are not intended to diagnose, treat, or cure any condition and do not replace the advice of a healthcare provider. OPTML does not offer medical advice, a diagnosis, medical treatment, or any form of medical opinion.