Nutrients system

Vitamin D (25-OH)

Vit D

The most accurate measure of your vitamin D status.

What is it

Vitamin D (25-OH) — in plain English.

25-hydroxyvitamin D is the storage form of vitamin D in the body and the standard marker for evaluating vitamin D status. It reflects intake from sun, food, and supplements over recent weeks.

Why it's measured

What Vit D can reveal.

Vitamin D has been associated with bone health, immune function, mood, and a range of other outcomes in published research. Deficiency is common in modern populations.

Reference range

Where most laboratories draw the standard line.

Standard laboratory reference

30 – 100 ng/mL

Reference ranges vary by laboratory. Your individual reference range will appear on your test report and should be interpreted by your physician in the context of your overall health profile.

What results may indicate

Higher vs. lower Vit D — at a high level.

Elevated

Very high values can warrant clinical evaluation. Most often reflects high-dose supplementation.

Lower

Has been associated with bone health concerns, reduced immune function, and mood changes in research literature.

These associations are general. They are not a personal diagnosis or prediction. Discuss your individual results with your physician in the context of your full health profile.

When it's measured

When Vit D is typically run.

Often measured annually or when deficiency is suspected.

Related markers

Often measured alongside Vit D.

Common questions

Questions people ask about Vitamin D (25-OH)

What is Vitamin D (25-OH)?

25-hydroxyvitamin D is the storage form of vitamin D in the body and the standard marker for evaluating vitamin D status. It reflects intake from sun, food, and supplements over recent weeks.

Why is Vitamin D (25-OH) measured?

It's one of the markers used to build a fuller picture of your health. On its own it tells you very little, so it's most informative when reviewed alongside related markers.

How is Vitamin D (25-OH) tested?

It's measured from a standard blood draw at Quest or LabCorp. Vitamin D (25-OH) is one of the markers included in the OPTML Apex Panel, where your results are read across systems and reviewed by a U.S.-licensed physician.

What should I do with my Vitamin D (25-OH) result?

Reference ranges vary by laboratory, and a single value rarely tells the whole story. Review your result with a physician in the context of your other markers, symptoms, and history.

Not sure which panel is right for you?

Vitamin D (25-OH) is one signal among many. Answer a few quick questions and we’ll point you to the panel that fits.

Measured in

Vit D is one of 160 biomarkers in the Apex Panel.

A complete look at your heart, hormones, metabolism, inflammation, and longevity systems — drawn at Quest or LabCorp, reviewed by a U.S.-licensed physician.

Explore the Apex Panel
160 biomarkers13 body systemsPhysician-reviewed
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This information is for general educational purposes only and is not medical advice. Lab results alone are not intended to diagnose, treat, or cure any condition and do not replace the advice of a healthcare provider. OPTML does not offer medical advice, a diagnosis, medical treatment, or any form of medical opinion.