Hormones system

PSA Total

PSA

A protein produced by the prostate, used in prostate cancer screening.

What is it

PSA Total — in plain English.

Prostate-specific antigen is a protein produced by prostate cells. PSA is used in screening and monitoring of prostate cancer, though levels can also rise from benign causes.

Why it's measured

What PSA can reveal.

PSA has been studied extensively in prostate cancer screening research. Clinical interpretation requires age and family history context.

Reference range

Where most laboratories draw the standard line.

Standard laboratory reference

< 4.0 ng/mL

Reference ranges vary by laboratory. Your individual reference range will appear on your test report and should be interpreted by your physician in the context of your overall health profile.

What results may indicate

Higher vs. lower PSA — at a high level.

Elevated

Warrants clinical evaluation. Can rise from benign prostatic hyperplasia, prostatitis, or cancer.

Lower

Is generally considered favorable.

These associations are general. They are not a personal diagnosis or prediction. Discuss your individual results with your physician in the context of your full health profile.

When it's measured

When PSA is typically run.

Used in prostate cancer screening, typically in men over 50 or earlier with family history.

Related markers

Often measured alongside PSA.

Common questions

Questions people ask about PSA Total

What is PSA Total?

Prostate-specific antigen is a protein produced by prostate cells. PSA is used in screening and monitoring of prostate cancer, though levels can also rise from benign causes.

Why is PSA Total measured?

It's one of the markers used to build a fuller picture of your health. On its own it tells you very little, so it's most informative when reviewed alongside related markers.

How is PSA Total tested?

It's measured from a standard blood draw at Quest or LabCorp. PSA Total is one of the markers included in the OPTML Apex Panel, where your results are read across systems and reviewed by a U.S.-licensed physician.

What should I do with my PSA Total result?

Reference ranges vary by laboratory, and a single value rarely tells the whole story. Review your result with a physician in the context of your other markers, symptoms, and history.

Not sure which panel is right for you?

PSA Total is one signal among many. Answer a few quick questions and we’ll point you to the panel that fits.

Measured in

PSA is one of 160 biomarkers in the Apex Panel.

A complete look at your heart, hormones, metabolism, inflammation, and longevity systems — drawn at Quest or LabCorp, reviewed by a U.S.-licensed physician.

Explore the Apex Panel
160 biomarkers13 body systemsPhysician-reviewed
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This information is for general educational purposes only and is not medical advice. Lab results alone are not intended to diagnose, treat, or cure any condition and do not replace the advice of a healthcare provider. OPTML does not offer medical advice, a diagnosis, medical treatment, or any form of medical opinion.